Trastuzumab Deruxtecan Superior to Trastuzumab Emtansine in Metastatic HER2-positive Breast Cancer
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Trastuzumab Deruxtecan Superior to Trastuzumab Emtansine in Metastatic HER2-positive Breast Cancer

Trastuzumab Deruxtecan Superior to Trastuzumab Emtansine in Metastatic HER2-positive Breast Cancer

In patients with HER2-positive metastatic breast cancer previously treated with trastuzumab and a taxane, the risk of disease progression or death was lower with trastuzumab deruxtecan than trastuzumab emtansine [Hazard ratio – 0.28 (p<0.001)]. The corresponding overall survival rate was 94.1% and 85.9% after 12 months, and the overall response was 79.7% and 34.2%. (Ref: Cortés J, et al. N Engl J Med March 24, 2022).

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